7 facts that you need to know about worldwide clinical trial!
The first Clinical Trial was done in 1747!
In 1747, A doctor named James Lind planned a several test on crew members of the British naval ship Salisbury in order to find out a solution for scurvy and what he discovered was that lemons and oranges were the most powerful fruits when it comes to treating the condition. Dr. Lind is known as the first physician who was able to conduct a completely controlled clinical trial. May 20 is celebrated as International Clinical Trials Day, as Dr. Lind’s started his clinical trial on that day in 1747.
Cost of clinical trials has become 13.27% higher in past few decades!
As of today, the cost that takes to develop a successful medicine can exceed $2.6 billion, compared to $179 million it used to take in the 1970s. This cost inflation is due to the advancement of technology and with technological breakthroughs in past 20 years, the entire pharmaceutical market of the world wide is predicted to reach an approximate value of $1.43 trillion by 2020.
Aspirin is 5000 years old medicine!
Aspirin is one of the most commonly used drugs in worldwide clinical trial. If you see the trend of worldwide clinical trial industry you will see that an estimated 700 to 1000 clinical trials are conducted every year. Researchers have traced back the usage of Aspirin to 3000 BC where Egyptians and Sumerians used willow as medicine circa. Since its discovery in 1899 by Bayer Aspirin has been the hottest topic for researchers.
The first genetically engineered drug that was introduced in markets was in 1982.
In 1982, FDA approved the world’s first genetically engineered drug or we can say medicine. Human insulin aka Humulin, was developed by Eli Lilly & Company and Genentech, it was the one of the biggest discovery if we talk about worldwide clinical trial. It was developed by inserting human genes that are responsible for insulin production into E.Coli bacteria, which then stimulates the bacteria to synthesize insulin.
Approval of more medicines can save many lives!
A total 293 medicines have been approved in past 10 years alone, that offers new hope to the patients with hard-to-treat diseases like cancer. The inventions of these medicines offer two main benefits to worldwide clinical trial industry: physical & mental well-being improvement of the society & hospitalization reduction.
The Drugs that are made for Neglected Diseases under initiative called DNDi plans to deliver 16 to18 new drugs for treatments by 2023, of which six are already available for diseases leishmaniasis, sleeping sickness (human African trypanosomiasis), Chagas disease, pediatric HIV, filarial diseases, mycetoma, and hepatitis C. It has been told that DNDi is also deploying global policy advocacy efforts to focus on the collection of a global fund for innovations like these in the importance of public health.
End of cancer is not DEATH anymore!!!
Worldwide clinical trials have improved that rate of childhood cancer survival. Childhood cancer survival rates have gone better from less than 10 percent which they were in the late 1950s to over 80 percent in the recent years, due in part to clinical trials. Worldwide clinical trials have also been making the method of cancer research better, turning it into more personal and tailored method to treat each and every person, one at a time, instead of the disease as a whole.
The placebo’s effect.
The term “placebo” was first talked about in medical literature during the early 1800s.In the “Hooper’s Medical Dictionary” of the year 1811 it is defined as “an epithet given to any medicine more to please than benefit the any patient.” It was only 52 years later that an american physician planned his first clinical study on the topic “dummy remedy” to compare it against the current treatment method.
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